HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 21539424, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methyl Isocyanate | HCID 12228 | — |
| Reactant | 2-Amino-4-(1,1-dimethylethyl)-3-thiophenecarbonitrile | HCID 596866 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 21539424 | HCID 21539424 | — |
Reaction Steps
A solution of 4 g 2-amino-3-cyano-4-t-butylthiophene, 1.27 g methyl isocyanate and 3 ml triethylamine in 20 ml dimethylformamide was heated at 130°C. for 3 hours and then allowed to stand at about 25°C. overnight. The dimethylformamide was removed by distillation and the residue was crystallized from ether to give the product, as a tan solid, m.p. 212°-214°C. The infrared spectrum of the product showed cyano absorption at 4.6 microns. Sulfur analysis for the product is tabulated in Table I.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03956315 |
| Source dataset | uspto-grants-1976_05 |
| ORD ID | ord-29fe9d9ff3f94f46a5d89010d05c1bce |
| Source note | uspto-grants-1976_05 |