Sulfuric Acid → 7-chloro-9H-dibenzo[b,f]imidazo[1,2-d][1,4]diazepine

HRID 1076205Notes

Reaction equation

HRID 1076205 reaction equation
CO[CH:3](OC)[CH2:4][NH:5][C:6]1[C:7]2[CH:21]=[CH:20][CH:19]=[CH:18][C:8]=2[NH:9][C:10]2[CH:16]=[C:15]([Cl:17])[CH:14]=[CH:13][C:11]=2[N:12]=1.S(=O)(=O)(O)O>>[Cl:17][C:15]1[CH:14]=[CH:13][C:11]2[N:12]3[CH:3]=[CH:4][N:5]=[C:6]3[C:7]3[CH:21]=[CH:20][CH:19]=[CH:18][C:8]=3[NH:9][C:10]=2[CH:16]=1

Participants

3

Reactant 2

HCID 1118Sulfuric AcidHCID 178495881HCID 178495881, compound

Product 1

HCID 123285207-chloro-9H-dibenzo[b,f]imidazo[1,2-d][1,4]diazepine

Procedure

In the manner given in Example 2, 7-chloro-[(5H-dibenzo[b,e][1,4]diazepin-11-yl)amino]acetaldehyde dimethyl acetal is treated with concentrated sulfuric acid to give 7-chloro-9H-dibenzo[b,f]imidazo[1,2-d][1,4]diazepine.

Sources & evidence

ORD record
ord-4cf81fa8c5a744f3a6b20de57634f4f6
Source dataset
uspto-grants-1976_05
Patent number
US03956297

Reaction notes

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