Sulfuric Acid → HCID 21539207, compound

HRID 1076207Notes

Reaction equation

HRID 1076207 reaction equation
CO[CH:3](OC)[CH2:4][NH:5][C:6]1[C:7]2[CH:24]=[CH:23][CH:22]=[CH:21][C:8]=2[NH:9][C:10]2[CH:16]=[CH:15][C:14]([C:17]([F:20])([F:19])[F:18])=[CH:13][C:11]=2[N:12]=1.S(=O)(=O)(O)O>>[F:18][C:17]([F:20])([F:19])[C:14]1[CH:15]=[CH:16][C:10]2[NH:9][C:8]3[CH:21]=[CH:22][CH:23]=[CH:24][C:7]=3[C:6]3[N:12]([CH:3]=[CH:4][N:5]=3)[C:11]=2[CH:13]=1

Participants

3

Reactant 2

HCID 1118Sulfuric AcidHCID 178495882HCID 178495882, compound

Product 1

HCID 21539207HCID 21539207, compound

Procedure

In the manner given in Example 5, 8-trifluoromethyl-[(5H-dibenzo[b,e][1,4]diazepin-11-yl)amino]acetaldehyde dimethyl acetal is treated with concentrated sulfuric acid to give 6-trifluoromethyl-9H-dibenzo[b,f]imidazo-[1,2-d][1,4]diazepine.

Sources & evidence

ORD record
ord-f2d87011eee54479acf4222dc08e1a5a
Source dataset
uspto-grants-1976_05
Patent number
US03956297

Reaction notes

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