4185-98-2 → HCID 21539683, compound

HRID 1076263Notes

Reaction equation

HRID 1076263 reaction equation
Cl.[N:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1C(=NO)Cl.Cl.C(=N[OH:22])(Cl)C1C=CN=CC=1.Cl.[C:24](=[N:32][OH:33])(Cl)[C:25]1[CH:30]=[CH:29][CH:28]=NC=1>>[N:2]1[CH:3]=[CH:4][C:5]([C:24]2[CH:25]=[C:30]([CH2:29][CH2:28][OH:22])[O:33][N:32]=2)=[CH:6][CH:7]=1

Participants

4

Procedure

By substituting an equimolar amount of picolinoyl chloride oxime hydrochloride or isonicotinoyl chloride oxime hydrochloride for the nicotinoyl chloride oxime hydrochloride employed in the above example, there is obtained the corresponding 3-(2-pyridyl)-5-isozazoleethanol and 3-(4-pyridyl)-5-isoxazoleethanol.

Sources & evidence

ORD record
ord-8581c986830c4779ba32ff4a66aa4b15
Source dataset
uspto-grants-1976_05
Patent number
US03956343

Reaction notes

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