4-Chlorobenzaldehyde → HCID 54524986, compound

Participants

Reaction Steps

A sodium hydroxide solution (8 ml., 20%) is added to a solution of p-chlorobenzaldehyde (20.4 g., 0.14 mole) and crude 3-phenyl-6-(p-methylphenyl)-5-hexen-2-one (Step A, above) in ethanol (350 ml.) with stirring. The off-white solid that separates on continued stirring is filtered, washed with cold ethanol and air-dried, yield 44 g., m.p. 114°-118°C. Recrystallization from ethanol gives material with m.p. 134°-136.5°C.

Provenance & Evidence