Hydroquinone → HCID 54481936, compound

Participants

Reaction Steps

In a 1 liter capacity round bottom flask equipped with a stirrer were put 90.5 g (1.0 mole) of acrylic acid chloride and 250 cc of acetonitrile and, as a polymerization-inhibitor, 0.5 g of hydroquinone, and the contents were cooled to 5°-10°C, and thereafter, 130 g (1.0 mole) of 2-morpholinoethylamine were added dropwise thereto in the course of 3 hours while stirring. Afterwards, the contents were stirred further for 2 hours at 40°-50°C. Next, the temperature of the reaction mixture was reduced to 15°-30°C and a solution of 40 g of sodium hydroxide in 100 cc of water was added thereto and the mixture then was stirred for 30 minutes. After removal of the sodium chloride which separated, 97.0 g (52.7%) of a fraction of 122°-124°C/0.05 mmHg were obtained.

Provenance & Evidence