Peracetic Acid → HCID 54081276, compound

Participants

Reaction Steps

A mixture of 118.8 g. of 7-(3,7-dimethyl-2,6-nonadienyloxy)-chromane, 26 g. of anhydrous sodium acetate in 910 ml. of chloroform is treated over a period of 1 hour with 80 g. of 40% peracetic acid while stirring and flushing with nitrogen at 0°-2°C. The resulting mixture is subsequently stirred for an additional 15 minutes. The mixture is washed successively with a saturated sodium chloride solution, 10% sodium bicarbonate 0.1-N sodium thiosulphate solution and water, dried over sodium sulphate and concentrated. By filtration over 600 g. of silica gel with hexane/ether (9:1) and subsequent molecular distillation, there is obtained 7-(6,7-epoxy-3,7-dimethyl-2-nonenyloxy)-chromane, nD20 = 1.5295.

Provenance & Evidence