Morpholine → Methanone, [4-(4-morpholinyl)-3-nitrophenyl]phenyl-

HRID 1076533Notes

Reaction equation

HRID 1076533 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:15]=[CH:16][C:17]=1Cl)[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:8])([O-:3])=[O:2].[NH:19]1[CH2:24][CH2:23][O:22][CH2:21][CH2:20]1>>[N+:1]([C:4]1[CH:5]=[C:6]([CH:15]=[CH:16][C:17]=1[N:19]1[CH2:24][CH2:23][O:22][CH2:21][CH2:20]1)[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:8])([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 8083MorpholineHCID 417434-Chloro-3-nitrobenzophenone

Product 1

HCID 2879429Methanone, [4-(4-morpholinyl)-3-nitrophenyl]phenyl-Yield 98%

Procedure

3-Nitro-4-chloro-benzophenone is reacted with morpholine as described in Example 7 to obtain 3-nitro-4-morpholino-benzophenone with a yield of 98% (compound B2, supra. The product melts at 103°C.

Sources & evidence

ORD record
ord-ce7e84be3f964c97bccd4aa0ec0cd973
Source dataset
uspto-grants-1976_05
Patent number
US03957777

Reaction notes

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