Sodium → HCID 135762629, compound

Participants

Reaction Steps

A solution of 8.9 g (385 millimoles) of sodium in 400 ml of methanol is added dropwise, while stirring, to a suspension of 93.9 g (350 millimoles) of 2-(4-nitrophenyl)-4H-1,3-benzoxazin-4-one and 58.1 g (192.5 millimoles) of guanyl urea sulfate in 1 liter of methanol. Subsequently, the mixture is refluxed for 30 minutes. After cooling of the mixture, the precipitate formed is suction-filtered, washed with water and methanol and dried at 70°C in a vacuum drying oven. The yield is 61.9 g (50.2 % of the theoretical yield). The 4-ureido-2-(2-hydroxyphenyl)-6-(4-nitrophenyl)-s-triazine obtained is a powder having a light yellow color and a melting point of 249°C (decomposition).

Provenance & Evidence