Chlorosulfonic acid → HCID 54418121, compound

HRID 1076544Notes

Reaction equation

HRID 1076544 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]([S:8][CH2:9][C:10]([NH:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[O:11])[CH:7]=1.[Cl:19][S:20](O)(=[O:22])=[O:21]>ClC1C=CC=CC=1Cl>[Cl:1][C:2]1[C:3]([S:20]([Cl:19])(=[O:22])=[O:21])=[CH:4][CH:5]=[C:6]([S:8][CH2:9][C:10]([NH:12][C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)=[O:11])[CH:7]=1

Participants

4

Reactant 2

HCID 24638Chlorosulfonic acidHCID 53984561HCID 53984561, compound

Product 1

HCID 54418121HCID 54418121, compound

Reagents, catalysts & solvents 1

HCID 72391,2-DichlorobenzeneSolvent

Procedure

A mixture of 250 g. (0.9 mole) of 5-chloro-2-(phenylthio)acetanilide and 116.52 g. (1.0 mole) of chlorosulfonic acid in 2.5 liters of o-dichlorobenzene is heated at 150°-160°C for 2 hours in an oil bath. The reaction mixture is cooled, washed with 1 liter of cold sodium carbonate solution, washed with water and then dried using magnesium sulfate. Removal of the solvent by distillation under vacuum yields the product.

Workup

  1. additionA mixture of 250 g
  2. temperatureThe reaction mixture is cooled
  3. washwashed with 1 liter of cold sodium carbonate solution
  4. washwashed with water
  5. customdried
  6. customRemoval of the solvent
  7. distillationby distillation under vacuum
  8. customyields the product

Sources & evidence

ORD record
ord-3f5c3737a1a84034a91e242c21fa47a0
Source dataset
uspto-grants-1976_05
Patent number
US03957769

Reaction notes

Loading…