反应详情

To 550.0 g of o-bromophenethyl alcohol, while stirring, is added, dropwise, 375.0 g of phosphorus tribromide. After stirring for three hours at room temperature, the reaction mixture is heated on a steam bath for three hours and then poured into 6 kg of crushed ice. The mixture is extracted with three 600 and two 200 ml portions of ether. The ether extracts are washed, dried, concentrated, and the residue is distilled to give 531.0 g of o-bromophenethyl bromide, bp. about 86°-88° (0.9mm), nD26 1.5922.

1. additionis added
2. temperaturethe reaction mixture is heated on a steam bath for three hours
3. extractionThe mixture is extracted with three 600 and two 200 ml portions of ether
4. washThe ether extracts are washed
5. customdried
6. concentrationconcentrated
7. distillationthe residue is distilled