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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 107657Generated: October 29, 2026

Dimethylamine → 4-(4-Chloro-2-fluoro-5-hydroxy-phenylamino)-7-(3-dimethylamino-propoxy)-6-methoxy-quinoline-3-carbonitrile

https://huagongshe.com/reaction/107657

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
ReactantSodium ionHCID 923—
ReactantTetrahydrofuranHCID 8028—
ReactantIodide IonHCID 30165—
Reactant4-(4-Chloro-2-fluoro-5-hydroxy-phenylamino)-7-(3-chloro-propoxy)-6-methoxy-quinoline-3-carbonitrileHCID 22466591—
Product4-(4-Chloro-2-fluoro-5-hydroxy-phenylamino)-7-(3-dimethylamino-propoxy)-6-methoxy-quinoline-3-carbonitrileHCID 10138437—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-79f9a662fb2443d1a268f2d9d0cda485
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)