HCID 6815530, compound → HCID 68138183, compound

HRID 1076657Notes

Reaction equation

HRID 1076657 reaction equation
[N+](C1OC([C:9]2[N:13]3N=C(Cl)C=C[C:12]3=[N:11][N:10]=2)=CC=1)([O-])=O.[N+:19]([C:22]1[O:36][C:25]([CH:26]=[N:27][NH:28][C:29]2[N:34]=[N:33][C:32](Cl)=[CH:31][CH:30]=2)=[CH:24][CH:23]=1)([O-:21])=[O:20].[C:37]([O-])(=O)C.C([O-])(=O)C.C([O-])(=O)C.C([O-])(=O)C.[Pb+4]>>[N+:19]([C:22]1[O:36][C:25]([C:26]2[N:34]3[N:33]=[C:32]([NH:10][N:11]=[CH:12][N:13]([CH3:9])[CH3:37])[CH:31]=[CH:30][C:29]3=[N:28][N:27]=2)=[CH:24][CH:23]=1)([O-:21])=[O:20]

Participants

4

Reactant 3

HCID 6815530HCID 6815530, compoundHCID 21537453HCID 21537453, compoundHCID 178418268HCID 178418268, compound

Product 1

HCID 68138183HCID 68138183, compound

Procedure

The preparation of 3-(5-nitro-2-furyl)-6-chloro-s-triazolo[4,3-b]pyridazine was carried out by the oxidative cyclization of 1-(5-nitro-furfurylidene)-2-(3-chloro-6-pyridazinyl) hydrazine (m.p. 250° - 254°C.) with lead tetraacetate. The yield was 79% and the product, after recrystallization from dimethyl formamide, melted at 222° - 226°C.

Workup

  1. customThe yield was 79% and the product, after recrystallization from dimethyl formamide, melted at 222° - 226°C.

Sources & evidence

ORD record
ord-fde3248034d94abdb030fdfa46a3c096
Source dataset
uspto-grants-1976_05
Patent number
US03957766

Reaction notes

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