Ammonia → HCID 20361997, compound

HRID 1076707Notes

Reaction equation

HRID 1076707 reaction equation
[CH3:1][CH:2]([N:11]1[C:15](=[O:16])[CH:14]=[C:13](Cl)[NH:12]1)[C:3]1[CH:8]=[CH:7][C:6]([CH3:9])=[C:5]([Cl:10])[CH:4]=1.[NH3:18]>C(O)C>[NH2:18][C:13]1[NH:12][N:11]([CH:2]([CH3:1])[C:3]2[CH:8]=[CH:7][C:6]([CH3:9])=[C:5]([Cl:10])[CH:4]=2)[C:15](=[O:16])[CH:14]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 20361913HCID 20361913, compound

Product 1

HCID 20361997HCID 20361997, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
150 °C

Procedure

0.2 mol of 1-(α-methyl-3-chloro-4-methylbenzyl)-3-chloropyrazol-5-one was dissolved in 100 ml of ethanol, 17 g of ammonia were added and the mixture was heated to 150°C for 2 hours in a stirred autoclave. After concentrating the reaction solution, the crude product was obtained. It was recrystallized twice from ethanol.

Workup

  1. concentrationAfter concentrating the reaction solution

Sources & evidence

ORD record
ord-08aa7b998a7a4b68a5fb5918655d75e8
Source dataset
uspto-grants-1976_05
Patent number
US03957814

Reaction notes

Loading…