Thionyl Chloride → HCID 178514950, compound

HRID 1076715Notes

Reaction equation

HRID 1076715 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]=[C:6]([NH:11][CH2:12][CH2:13][CH2:14]O)[C:5]2([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[OH:16].S(Cl)([Cl:25])=O>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]=[C:6]([NH:11][CH2:12][CH2:13][CH2:14][Cl:25])[C:5]2([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[OH:16]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 178520833HCID 178520833, compound

Product 1

HCID 178514950HCID 178514950, compound

Procedure

Reaction of 5-chloro-2-(3-hydroxypropylamino)-3-phenyl-3H-indol-3-ol with thionylchloride by a procedure analogous to that described in Example 2 gives 5-chloro-2-(3-chloropropylamino)-3-phenyl-3H-indol-3-ol.

Sources & evidence

ORD record
ord-ba52880300174eeb8f489aaf78995832
Source dataset
uspto-grants-1976_05
Patent number
US03957819

Reaction notes

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