Thionyl Chloride → HCID 178490036, compound

HRID 1076721Notes

Reaction equation

HRID 1076721 reaction equation
[CH2:1]([C:10]1([OH:24])[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[N:12]=[C:11]1[NH:19][CH2:20][CH2:21][CH2:22]O)[C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([O:8][CH3:9])[CH:3]=1.S(Cl)([Cl:27])=O>>[CH2:1]([C:10]1([OH:24])[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[N:12]=[C:11]1[NH:19][CH2:20][CH2:21][CH2:22][Cl:27])[C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([O:8][CH3:9])[CH:3]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 178490037HCID 178490037, compound

Product 1

HCID 178490036HCID 178490036, compound

Procedure

Reaction of 3-(m-anisyl)-2-(3-hydroxypropylamino)-3H-indol-3-ol with thionylchloride by a procedure analogous to that described in Example 2 gives 3-(m-anisyl)-2-(3-chloropropylamino)-3H-indol-3-ol.

Sources & evidence

ORD record
ord-563cb18a1f8a40cfa48c20568f09795e
Source dataset
uspto-grants-1976_05
Patent number
US03957819

Reaction notes

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