HCID 21538227, compound → HCID 12790678, compound

Participants

Reaction Conditions

Reaction Steps

4.3 Parts of 2,3,5-trimethyl-6-(5',5'-dicarboxy-3'-methylpentyl)-1,4-benzoquinone (Formula (IV) wherein R=H3C; Z=H) obtained in Reference Example 1 is heated at 140°C for 1 hour. It is then subjected to thin-layer chromatography with chloroform-ethanol (19:1) as the developer and recrystallized from ligroine. Th described procedure gives 2.97 parts of 2,3,5-trimethyl-6-(5'-carboxy-3'-methylpentyl)-1,4-benzoquinone (Formula (I) wherein R=H3C; Z=H) as yellowish needles. melting point 58°C-61°C.

Provenance & Evidence