HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 21538285, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 2-Bromopropane | HCID 6358 | — |
| Reactant | 2-(4-Aminophenyl)propanoate | HCID 21538282 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 21538285 | HCID 21538285 | — |
Reaction Steps
A mixture of 2-(p-aminophenyl)propionate (5.4 g), isopropyl bromide (5g), pyridine (5 ml) and ethanol (80 ml) is boiled during 16 hours. The reaction mixture is concentrated in vacuo, taken up into water, extracted with ether, dried, after which the solvent is removed. Chromatography over silica gives 2.2 g of methyl 2-(p-isopropylaminophenyl)propionate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03957850 |
| Source dataset | uspto-grants-1976_05 |
| ORD ID | ord-08de3536df764453ba6e1198f9160c2b |
| Source note | uspto-grants-1976_05 |