Hydrochloric Acid → HCID 54454409, compound

Participants

Reaction Conditions

Reaction Steps

5.8 G of 2-(4-chlorophenoxy)butyryl chloride (0.025 mol) are added dropwise, with stirring and whilst cooling with an ice bath at 0°C and working under nitrogen, to 3.65 g (0.025 mol) of indane-1,3-dione in 20 ml of pyridine containing two drops of piperidine. After stirring the mixture for 18 hours, it is poured onto ice and acidified with hydrochloric acid, and the resulting mixture is ectracted with chloroform. After evaporating the solvent, the residue is crystallised from ethyl acetate to give 1.55 g of pure 2-[2'-(4"-chlorophenoxy)butyryl]indane-1,3-dione, melting point 132°C. Empirical formula: C19H15O4Cl; molecular Weight: 342.79; Elementary analysis:

Provenance & Evidence