Acetic Acid → HCID 527056, compound

Participants

Reaction Steps

10 ml of acetic anhydride were first added to a solution kept at 10° of 3.5 g of Na2Cr2O7 .2H2O in 10 ml of acetic acid and the obtained mixture was stirred for one hour. A solution of 2.1 g of 2,6,6-trimethyl-1-(but-2-enoyl)-cyclohex-2-ene [prepared according to the method described in Helv. Chim. Acta 53, 541 (1970)], in 10 ml of acetic anhydride was then added to the above mixture. After having been stirred overnight at room temperature, the reaction mixture was then poured onto crushed ice and extracted with ether. After the usual treatments of washing, drying and evaporation, there was obtained 2.0 g of crude material containing 80 % of the desired keto compound.

Provenance & Evidence