HCID 28117411, compound → HCID 178477393, compound

HRID 1076821Notes

Reaction equation

HRID 1076821 reaction equation
[NH2:1][CH:2]1[C:20](=[O:21])[N:4]2[C:5]([C:17]([OH:19])=[O:18])=[C:6]([CH:9]([S:11][C:12]3[NH:16][N:15]=[N:14][N:13]=3)[CH3:10])[CH2:7][S:8][C@H:3]12.[C:22]([CH2:24][S:25][CH2:26][C:27]([O-])=[O:28])#[N:23]>>[C:22]([CH2:24][S:25][CH2:26][C:27]([NH:1][CH:2]1[C:20](=[O:21])[N:4]2[C:5]([C:17]([OH:19])=[O:18])=[C:6]([CH:9]([S:11][C:12]3[NH:13][N:14]=[N:15][N:16]=3)[CH3:10])[CH2:7][S:8][C@H:3]12)=[O:28])#[N:23]

Participants

3

Reactant 2

HCID 28117411HCID 28117411, compoundHCID 1784773817-Amino-3-(1-methyl-1H-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid

Product 1

HCID 178477393HCID 178477393, compound

Procedure

The title compound was prepared by the reaction of 7-amino-3-(1-methyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid (3.28 g, 10 mmol) and N-hydroxysuccininimidyl cyanomethylmercaptoacetate (3.4 g, 15 mmol) by the procedure of Example 1.

Sources & evidence

ORD record
ord-bfeacdaa4d52411b95c13cdc462e151d
Source dataset
uspto-grants-1976_05
Patent number
US03957984

Reaction notes

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