HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexanone → HCID 178429192, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexanone | HCID 7967 | — |
| Reactant | Ethyl Acetoacetate | HCID 8868 | — |
| Reactant | Ammonium Acetate | HCID 517165 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178429192 | HCID 178429192 | 5% |
Reaction Steps
98.15 G. (1.0 mole) of cyclohexanone, 130 g. (1.0 mole) of ethylacetoacetate and 77.1 g. (1.0 mole) of ammonium acetate are heated at reflux for 14 hours. The reaction mixture is cooled in ice and diluted with water. The resultant precipitate is collected by filtration, washed with ether and dried in air affording 8.0 g (5%) of 2-hydroxy-4-methyl-5,6,7,8-tetrahydroquinoline, m.p. 250°-252°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03957997 |
| Source dataset | uspto-grants-1976_05 |
| ORD ID | ord-54e9386f7c714e03a12523ac335c1f0b |
| Source note | uspto-grants-1976_05 |