HuagongsheHuagongshe Chemistry Print Report · For research reference only
Succinic Acid → 5-Methoxy-2-[4-(2-pyrrolidin-1-ylethoxy)anilino]benzothiazole succinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Succinic Acid | HCID 1110 | — |
| Reactant | Benzothiazole, 5-methoxy-2-(beta-(1-pyrrolidinyl)-p-phenetidino)- | HCID 38054 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 5-Methoxy-2-[4-(2-pyrrolidin-1-ylethoxy)anilino]benzothiazole succinate | HCID 21538597 | — |
Reaction Steps
A solution of 5-methoxy-2-[4-(2-pyrrolidin-1-ylethoxy)anilino]benzothiazole (0.738 g.) in ethanol (30 ml.) is treated at room temperature with a solution of succinic acid (0.236 g.) in ethanol 3.5 ml.). After 1 hour the solution is diluted with ether (70 ml.) and then kept at 0° - 10°C. overnight. The resulting precipitate is collected by filtration and dried to give 5-methoxy-2-[4-(2-pyrrolidin-1-ylethoxy)anilino]benzothiazole succinate, m.p. 150° - 153°C. Elemental analysis satisfactory for C24H29N3O6S.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03957999 |
| Source dataset | uspto-grants-1976_05 |
| ORD ID | ord-ab487f54955646c385305d372c4e116b |
| Source note | uspto-grants-1976_05 |