HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-nitrobenzaldehyde → HCID 70631679, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-nitrobenzaldehyde | HCID 72933 | — |
| Reactant | Carbamimidoyl-acetic acid ethyl ester | HCID 4599837 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 70631679 | HCID 70631679 | 48% |
Reaction Steps
Upon boiling a solution of 9.3 g 3-nitro-6-chlorobenzaldehyde and 13.0 g amidinoacetic acid ethyl ester in 150 ml ethanol for 2 hours, 2,6-diamino-4-(3-nitro-6-chlorophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester of m.p. 130°C (ethanol) is obtained. Yield: 48% of theory.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03957998 |
| Source dataset | uspto-grants-1976_05 |
| ORD ID | ord-18a7f8399ca34687b904094452336ba6 |
| Source note | uspto-grants-1976_05 |