Fumarate(1-) → HCID 53872737, compound

HRID 1076885Notes

Reaction equation

HRID 1076885 reaction equation
[F:1][C:2]1[CH:3]=[C:4]2[C:12](=[CH:13][CH:14]=1)[C:7]1([CH2:11][CH2:10][NH:9][CH2:8]1)[CH2:6][CH:5]2[OH:15].[C:16]([OH:23])(=O)/[CH:17]=[CH:18]/[C:19]([O-])=O>>[F:1][C:2]1[CH:3]=[CH:4][C:12]([C:16](=[O:23])[CH2:17][CH2:18][CH2:19][N:9]2[CH2:10][CH2:11][C:7]3([C:12]4[C:4](=[CH:3][C:2]([F:1])=[CH:14][CH:13]=4)[CH:5]([OH:15])[CH2:6]3)[CH2:8]2)=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 6183479Fumarate(1-)HCID 21538668HCID 21538668, compound

Product 1

HCID 53872737HCID 53872737, compound

Procedure

5-Fluorospiro[indan-1,3'-pyrrolidin]-3-ol is reacted in a manner analogous to that described in Example 1(A) or Example 2(A). The hydrogen fumarate of the title compound has a M.P. of 143°-145° (from ethanol/ether).

Sources & evidence

ORD record
ord-dc71373011f94646b7a34e4bea727425
Source dataset
uspto-grants-1976_05
Patent number
US03958003

Reaction notes

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