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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1076993Generated: October 30, 2026

1,4-Dibromobutane → 2-(5-Bromopentyl)benzo[de]isoquinoline-1,3-dione

https://huagongshe.com/reaction/1076993

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-DibromobutaneHCID 8056—
Reactant1,5-DibromopentaneHCID 8100—
ReactantN-[1-[4-(1,3-dihydro-1,3-dioxo-2H-benz[de]isoquinolin-2-yl)butyl]-4-piperidinyl]-N-phenylpropanamide, hydrochlorideHCID 131710247—
Product2-(5-Bromopentyl)benzo[de]isoquinoline-1,3-dioneHCID 16638791—

Reaction Steps

Following the procedure of part (a) of example 31 but substituting 1,5-dibromopentane for the 1,4-dibromobutane, one obtains 2-(5-bromopentyl)-1H-benz[de]isoquinoline-1,3(2H)-dione; m.p. 113°-115°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03959286
Source datasetuspto-grants-1976_05
ORD IDord-69273092194f454d881f320945cb2ec0
Source noteuspto-grants-1976_05