HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-bromobutyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione → N-[1-[5-(1,3-dihydro-1,3-dioxo-2H-benz[de]isoquinolin-2-yl)pentyl]-4-piperidinyl]-N-phenylpropanamide, hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-bromobutyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione | HCID 2782360 | — |
| Reactant | 2-(5-Bromopentyl)benzo[de]isoquinoline-1,3-dione | HCID 16638791 | — |
| Reactant | N-[1-[4-(1,3-dihydro-1,3-dioxo-2H-benz[de]isoquinolin-2-yl)butyl]-4-piperidinyl]-N-phenylpropanamide, hydrochloride | HCID 131710247 | — |
| Product | N-[1-[5-(1,3-dihydro-1,3-dioxo-2H-benz[de]isoquinolin-2-yl)pentyl]-4-piperidinyl]-N-phenylpropanamide, hydrochloride | HCID 131710248 | — |
Reaction Steps
Following the procedure of part (b) of example 31 but substituting 2-(5-bromopentyl)-1H-benz[de]isoquinoline-1,3(2H)-dione for the 2-(4-bromobutyl)-1H-benz[de]isoquinoline-1,3(2H)-dione, one obtains N-[1-[5-(1,3-dihydro- 1,3-dioxo-2H-benz[de]isoquinolin-2-yl)pentyl]-4-piperidinyl]-N-phenylpropanamide, hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03959286 |
| Source dataset | uspto-grants-1976_05 |
| ORD ID | ord-e05cfdb7a7b14b1595d71d82337f8f2a |
| Source note | uspto-grants-1976_05 |