HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-bromobutyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione → N-[1-[6-(1,3-dihydro-1,3-dioxo-2H-benz[de]isoquinolin-2-yl)hexyl]-4-piperidinyl]-N-phenylpropanamide, hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-bromobutyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione | HCID 2782360 | — |
| Reactant | 2-(6-bromohexyl)-1H-benz[de]isoquinoline-1,3(2H)-dione | HCID 20364507 | — |
| Reactant | N-[1-[4-(1,3-dihydro-1,3-dioxo-2H-benz[de]isoquinolin-2-yl)butyl]-4-piperidinyl]-N-phenylpropanamide, hydrochloride | HCID 131710247 | — |
| Product | N-[1-[6-(1,3-dihydro-1,3-dioxo-2H-benz[de]isoquinolin-2-yl)hexyl]-4-piperidinyl]-N-phenylpropanamide, hydrochloride | HCID 131710249 | — |
Reaction Steps
Following the procedure of part (b) of example 31 but substituting 2-(6-bromohexyl)-1H-benz[de]isoquinoline-1,3(2H)-dione for the 2-(4-bromobutyl)-1H-benz[de]isoquinoline-1,3-(2H)-dione, one obtains N-[1-[6-(1,3-dihydro-1,3-dioxo-2H-benz[de]isoquinolin-2-yl)hexyl]-4-piperidinyl]-N-phenylpropanamide, hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03959286 |
| Source dataset | uspto-grants-1976_05 |
| ORD ID | ord-d3ed46a9a7fa44108b6289558755e702 |
| Source note | uspto-grants-1976_05 |