Amphetamine → HCID 68147465, compound

HRID 1077080Notes

Reaction equation

HRID 1077080 reaction equation
CC(N)CC1C=CC=CC=1.BrCCOCCCC(C1C=CC=CC=1)=O.Cl.[CH3:27][C:28]1([CH:50]=[CH:49][CH:48]=[CH:47][CH2:46]1)[CH2:29][CH2:30][NH:31][CH2:32][CH2:33][O:34][CH2:35][CH2:36][CH2:37][C:38]([C:40]1[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=1)=[O:39]>C(O)C>[CH3:27][C:28]1([CH:46]=[CH:47][CH:48]=[CH:49][CH2:50]1)[CH2:29][CH2:30][NH:31][CH2:32][CH2:33][O:34][CH2:35][CH2:36][CH2:37][C:38]([C:40]1[CH:41]=[CH:42][CH:43]=[CH:44][CH:45]=1)=[O:39]

Participants

5

Reactant 3

HCID 3007AmphetamineHCID 21535925HCID 21535925, compoundHCID 68148563HCID 68148563, compound

Product 1

HCID 68147465HCID 68147465, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

α-methyl-phenethylamine (0.02 mole) and 4-(2-bromo-ethoxy)-butyrophenone (0.01 mole) dissolved in ethanol (20 cc) are refluxed during 15 hours. The procedure described in Example 1 is then used. 4-[2-(1-methyl-phenethylamino)-ethoxy]-butyrophenone hydrochloride melts at 195°-197°C.

Workup

  1. temperatureare refluxed during 15 hours

Sources & evidence

ORD record
ord-a8c9b4f48fb24ef78af7f5d0234f2828
Source dataset
uspto-grants-1976_05
Patent number
US03959359

Reaction notes

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