Trifluoroborane Hydrofluoride → 4-Bromo-2-fluoro-1,1'-biphenyl

HRID 1077085Notes

Reaction equation

HRID 1077085 reaction equation
N[C:2]1[CH:7]=[C:6]([Br:8])[CH:5]=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.B(F)(F)[F:16].F>>[Br:8][C:6]1[CH:5]=[CH:4][C:3]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[C:2]([F:16])[CH:7]=1

Participants

3

Reactant 2

HCID 9855450Trifluoroborane HydrofluorideHCID 214242274-Bromo[1,1′-biphenyl]-2-amine

Product 1

HCID 5210634-Bromo-2-fluoro-1,1'-biphenyl

Procedure

2-Amino-4-bromo-biphenyl was subjected to a Schiemann reaction using hydrofluoroboric acid. The product had a b.p. of 106°-109°C./0.6mm, and a m.p. of 38°-39°C.

Sources & evidence

ORD record
ord-9c41c998231c4cb882ff6aee5fe6501e
Source dataset
uspto-grants-1976_05
Patent number
US03959364

Reaction notes

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