Ammonia → (17Beta)-13-Ethyl-3-methoxygona-2,5(10)-dien-17-ol

Participants

Role	Name	HCID	Charge
Reactant	Ammonia	HCID 222	—
Reactant	Lithium	HCID 3028194	—
Reactant	13beta-(3-Dimethylaminopropyl)-1,3-dimethoxy-gona-1,3,5(10)-trien 17beta-ol	HCID 22790383	—
Reactant	13beta-(3-Dimethylaminopropyl)-1,3-dimethoxy-gona-1(10),3-dien-17beta-ol	HCID 68143588	—
Solvent	Tetrahydrofuran	HCID 8028	—
Product	(17Beta)-13-Ethyl-3-methoxygona-2,5(10)-dien-17-ol	HCID 101950	—

Reaction Steps

To prepare 13β-(3-dimethylaminopropyl)-1,3-dimethoxy-gona-1(10),3-dien-17β-ol react 13β-(3-dimethylaminopropyl)-1,3-dimethoxy-gona-1,3,5(10)-trien 17β-ol in tetrahydrofuran with lithium in liquid ammonia according to the manipulative procedure described above.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US03959322
Source dataset	uspto-grants-1976_05
ORD ID	ord-86e9add537f24d60967d2845bf4d7c74
Source note	uspto-grants-1976_05