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HRID1077220

反应详情

EQUATION

反应方程式

HRID 1077220 的结构方程式

REACTANTS

反应物

1
结构：CC[C@]12CCC3=C(CC(C)c4cc(OC)ccc43)C1=CCC21OCCO1
HCID68145250

未命名化合物

PRODUCTS

生成物

1
结构：CC[C@]12CCC3=C(CC(C)c4cc(OC)ccc43)[C@@H]1CCC21OCCO1
HCID68144184

未命名化合物

收率 71.5%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：O=C([O-])[O-].[Ca+2].[Pd]
催化剂HCID12000666

未命名化合物

结构：c1ccccc1
溶剂HCID241

Benzene

C6H6

PROCEDURE

实验过程

Monohydrogenate dl-3-methoxy-6-methyl-17,17-ethylenedioxy-13-ethylgona-1,3,5(10),8,14-pentaene (15.3 g) in benzene (300 cc) in the presence of 2% Pd/CaCO3 (5.0 g). Filter, remove the benzene under reduced pressure and recrystallize from 95% ethanol (110 cc) to yield the dl-3-methoxy-6-methyl-17,17-ethylenedioxy-13-ethylgona-1,3,5(10),8-tetraene (11.0 g), m.p. 122°-124°, diamond shaped plates, λ max. EtOH 280 mμ (ε15,140).

WORKUP

后处理

  1. filtrationFilter
  2. customremove the benzene under reduced pressure
  3. customrecrystallize from 95% ethanol (110 cc)