2-Methylbenzaldehyde → HCID 70617040, compound

HRID 1077257Notes

Reaction equation

HRID 1077257 reaction equation
[ClH:1].Cl.[NH2:3][N:4]1[CH:8]=[N:7][N:6]=[C:5]1[NH:9][NH2:10].[C:11]1([CH3:19])[C:12]([CH:17]=O)=[CH:13][CH:14]=[CH:15][CH:16]=1>C(O)C>[ClH:1].[NH2:3][N:4]1[CH:8]=[N:7][N:6]=[C:5]1[NH:9][N:10]=[CH:19][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[CH3:17]

Participants

4

Reactant 2

HCID 107222-MethylbenzaldehydeHCID 13931004HCID 13931004, compound

Product 1

HCID 70617040HCID 70617040, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 14.0 g (0.075 mole) of 4-amino-3-hydrazino-1, 2,4-triazole dihydrochloride in 200 ml of 75 percent ethanol was added 9.0 g (0.075 mole) of o-tolualdehyde. The mixture was stirred and heated at reflux for 1.5 hour. The solution was cooled and the precipitate formed collected by filtration and washed with ether. Yield: 18.4 g, m.p. 230°-232° (D). After recrystallization from aqueous ethanolisopropyl ether the product melts at 233°-234° (D).

Workup

  1. temperatureheated
  2. temperatureat reflux for 1.5 hour
  3. temperatureThe solution was cooled
  4. customthe precipitate formed
  5. filtrationcollected by filtration
  6. washwashed with ether
  7. customAfter recrystallization from aqueous ethanolisopropyl ether the product melts at 233°-234° (D)

Sources & evidence

ORD record
ord-4d915622b48945fd923b2e5cc54d8cf9
Source dataset
uspto-grants-1976_05
Patent number
US03959476

Reaction notes

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