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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1077262Generated: October 30, 2026

2-Methylbenzaldehyde → HCID 12448677, compound

https://huagongshe.com/reaction/1077262

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MethylbenzaldehydeHCID 10722—
ReactantCarbamimidoyl-acetic acid ethyl esterHCID 4599837—
SolventEthanolHCID 702—
ProductHCID 12448677HCID 1244867767%

Reaction Steps

Upon boiling a solution of 6.0 g 2-methylbenzaldehyde and 13.0 g amidinoacetic acid ethyl ester in 150 ml ethanol for two hours, 2,6-diamino-4-(2-methylphenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester of m.p. 158°C (ethanol) is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03959474
Source datasetuspto-grants-1976_05
ORD IDord-b679486af10244f6bffa130b17a09888
Source noteuspto-grants-1976_05