HRID1077267

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID4436645

4,6-dimethoxypyrimidine-5-carbaldehyde

C7H8N2O3

HCID4599837

Carbamimidoyl-acetic acid ethyl ester

C5H10N2O2

PRODUCTS

生成物

结构：CCOC(=O)C1=C(N)NC(N)=C(C(=O)OCC)C1c1c(OC)ncnc1OC

HCID70631685

未命名化合物

收率 56%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID702

Ethanol

C2H6O

2 次

PROCEDURE

实验过程

Upon heating a solution of 8.4 g. 4,6-dimethoxypyrimidine-5-aldehyde and 13.0 g amidinoacetic acid ethyl ester in 150 ml ethanol for two hours, 2,6-diamino-4-(4,6-dimethoxypyrimid-5-yl)-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester of m.p. 219°C (ethanol) is obtained.

WORKUP

后处理

temperatureUpon heating a solution of 8.4 g