1-Benzyl-4-piperidone → HCID 21536114, compound
Reaction equation
[CH3:1][O:2][CH:3]([C:12]1[CH:17]=[CH:16][C:15]([F:18])=[CH:14][CH:13]=1)[C:4]1[CH:9]=[CH:8][C:7]([F:10])=[CH:6][C:5]=1Br.[CH2:19]([N:26]1[CH2:31][CH2:30]C(=O)[CH2:28][CH2:27]1)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[CH2:19]([N:26]1[CH2:31][CH2:30][C:1]2([C:9]3[C:4](=[CH:5][CH:6]=[C:7]([F:10])[CH:8]=3)[CH:3]([C:12]3[CH:17]=[CH:16][C:15]([F:18])=[CH:14][CH:13]=3)[O:2]2)[CH2:28][CH2:27]1)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1Participants
3
Procedure
By following the manipulative procedure described above in Example 45, 2-bromo-4,4'-difluorobenzhydryl methyl ether and 1-benzyl-4-piperidone are reacted to produce an oil.
Workup
- customare reacted
- customto produce an oil
Sources & evidence
- ORD record
- ord-a2f6587b2a084999ba2e75645c5e3080
- Source dataset
- uspto-grants-1976_05
- Patent number
- US03959475
Reaction notes
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