Methanol → HCID 21536120, compound

Participants

Reaction Steps

A solution of 2.5 g. of 1'-(2-benzoylethyl)-1,3-dihydro-3-phenylspiro[isobenzofuran-1,4'-piperidine], (Example 107), 30 ml. of methanol, and 0.35 g. of sodium borohydride is stirred at room temperature for 4 hours, diluted with water, and extracted with chloroform. The chloroform solution is dried over sodium sulfate and concentrated to provide 1,3-dihydro-1'-(3-hydroxy-3-phenylpropyl)-3-phenylspiro[isobenzofuran-1,4'-piperidine].

Provenance & Evidence