HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-(Dimethylamino)-8-ethoxycarbonyl-1,2,3,4-tetrahydrocarbazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 3-(Dimethylamino)-8-carboxy-1,2,3,4-tetrahydrocarbazole | HCID 12891862 | — |
| Reactant | 3-(Dimethylamino)-8-ethoxycarbonyl-1,2,3,4-tetrahydrocarbazole hydrochloride | HCID 23470278 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-(Dimethylamino)-8-ethoxycarbonyl-1,2,3,4-tetrahydrocarbazole | HCID 12891787 | — |
Reaction Steps
A solution of 4.5 g. of 3-(dimethylamino)-8-carboxy-1,2,3,4-tetrahydrocarbazole (Example 39) in 150 ml. of 5-N hydrogen chloride in ethyl alcohol was heated under reflux for thirty hours. The solution was evaporated to dryness under reduced pressure and the residue was recrystallized from ethanol to give 3 g. of 3-(dimethylamino)-8-ethoxycarbonyl-1,2,3,4-tetrahydrocarbazole hydrochloride, m.p. 263°-264°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03959309 |
| Source dataset | uspto-grants-1976_05 |
| ORD ID | ord-bc4933749f104025a3fb85685e23a41f |
| Source note | uspto-grants-1976_05 |