HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Dimethylamino)-8-ethoxycarbonyl-1,2,3,4-tetrahydrocarbazole → 3-(Dimethylamino)-8-hydroxymethyl-1,2,3,4-tetrahydrocarbazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Dimethylamino)-8-ethoxycarbonyl-1,2,3,4-tetrahydrocarbazole | HCID 12891787 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-(Dimethylamino)-8-hydroxymethyl-1,2,3,4-tetrahydrocarbazole | HCID 12891868 | — |
Reaction Steps
Following a procedure similar to that described in Example 55 and using 2.4 g. of 3-(dimethylamino)-8-ethoxycarbonyl-1,2,3,4-tetrahydrocarbazole (Example 44), 1.6 g. of lithium aluminum hydride and 150 ml. of dry tetrahydrofuran there was obtained, after successive recrystallizations from isopropyl alcohol and ethyl alcohol, 0.56 g. of 3-(dimethylamino)-8-hydroxymethyl-1,2,3,4-tetrahydrocarbazole, m.p. 227°-230°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03959309 |
| Source dataset | uspto-grants-1976_05 |
| ORD ID | ord-2d90f1ca5c5e46399f8bdf950aeefafd |
| Source note | uspto-grants-1976_05 |