1-Fluoro-5-methyl-2,4-dinitrobenzene → 4-Fluoro-6-methylbenzene-1,3-diamine

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Reaction Steps

2 g (0.01 ml) 5-fluoro-2,4-dinitrotoluene from Step 1 are hydrated with catalytic amounts of palladium/carbon (10% Pd) in 50 ml absolute ethanol. After removing the catalyst by filtration, the solvent is completely removed by distillation and the obtained product is recrystallized from toluene. 0.7 g (50% of theory) 5-fluoro-2,4-diaminotoluene are obtained which melts at 112° C. accompanied by decomposition.

Provenance & Evidence