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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1077462Erstellt: 25. Oktober 2026

3-(2-Chlorophenyl)acrylic acid → 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(2-chlorophenyl)ethenyl)-1,3-dipropyl-, (E)-

https://huagongshe.com/reaction/1077462

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt3-(2-Chlorophenyl)acrylic acidHCID 19567—
Edukt5,6-Diamino-1,3-dipropyl-2,4(1H,3H)-pyrimidinedioneHCID 5098605—
Produkt1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(2-chlorophenyl)ethenyl)-1,3-dipropyl-, (E)-HCID 644878882%

Reaktionsschritte

Substantially the same procedure as in Reference Example 1 was repeated using 3.00 g (13.3 mmol) of 5,6-diamino-1,3-dipropyluracil and 2.67 g (14.6 mmol) of 2-chlorocinnamic acid. Then, the resultant crude crystals were recrystallized from toluene to give 3.72 g (yield 82%) of Compound 41 as white needles.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05543415
Quelldatensatzuspto-grants-1996_08
ORD IDord-6cb0ca7eea2644239de851c1b8a1ef2b
Quellennotizuspto-grants-1996_08