HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-(2-Chlorophenyl)acrylic acid → 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(2-chlorophenyl)ethenyl)-1,3-dipropyl-, (E)-
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-(2-Chlorophenyl)acrylic acid | HCID 19567 | — |
| Edukt | 5,6-Diamino-1,3-dipropyl-2,4(1H,3H)-pyrimidinedione | HCID 5098605 | — |
| Produkt | 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(2-chlorophenyl)ethenyl)-1,3-dipropyl-, (E)- | HCID 6448788 | 82% |
Reaktionsschritte
Substantially the same procedure as in Reference Example 1 was repeated using 3.00 g (13.3 mmol) of 5,6-diamino-1,3-dipropyluracil and 2.67 g (14.6 mmol) of 2-chlorocinnamic acid. Then, the resultant crude crystals were recrystallized from toluene to give 3.72 g (yield 82%) of Compound 41 as white needles.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05543415 |
| Quelldatensatz | uspto-grants-1996_08 |
| ORD ID | ord-6cb0ca7eea2644239de851c1b8a1ef2b |
| Quellennotiz | uspto-grants-1996_08 |