HuagongsheHuagongshe Chemistry Print Report · For research reference only
5,6-Diamino-1,3-diethyluracil → 1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(2,5-dimethyl-4-methoxy)phenyl)ethenyl)-, (E)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5,6-Diamino-1,3-diethyluracil | HCID 4572133 | — |
| Reactant | 4-Methoxy-2,5-dimethylcinnamic acid | HCID 5199898 | — |
| Product | 1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(2,5-dimethyl-4-methoxy)phenyl)ethenyl)-, (E)- | HCID 6448859 | 52.3% |
Reaction Steps
Substantially the same procedure as in Reference Example 70 was repeated using 2.5 g (12.6 mmol) of 5,6-diamino-1,3-diethyluracil and 2.9 g (13.9 mmol) of 4-methoxy-2,5-dimethylcinnamic acid. Then, the resultant crude crystals were recrystallized from dioxane/water to give 2.43 g (yield 52%) of Compound 83 as white crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05543415 |
| Source dataset | uspto-grants-1996_08 |
| ORD ID | ord-ce30f946fd434da3aab423e491919b43 |
| Source note | uspto-grants-1996_08 |