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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1077483Generated: October 25, 2026

5,6-Diamino-1,3-diethyluracil → 1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(2,5-dimethyl-4-methoxy)phenyl)ethenyl)-, (E)-

https://huagongshe.com/reaction/1077483

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5,6-Diamino-1,3-diethyluracilHCID 4572133—
Reactant4-Methoxy-2,5-dimethylcinnamic acidHCID 5199898—
Product1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(2,5-dimethyl-4-methoxy)phenyl)ethenyl)-, (E)-HCID 644885952.3%

Reaction Steps

Substantially the same procedure as in Reference Example 70 was repeated using 2.5 g (12.6 mmol) of 5,6-diamino-1,3-diethyluracil and 2.9 g (13.9 mmol) of 4-methoxy-2,5-dimethylcinnamic acid. Then, the resultant crude crystals were recrystallized from dioxane/water to give 2.43 g (yield 52%) of Compound 83 as white crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05543415
Source datasetuspto-grants-1996_08
ORD IDord-ce30f946fd434da3aab423e491919b43
Source noteuspto-grants-1996_08