3-(4-Ethoxyphenyl)prop-2-enoic acid → 1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(4-ethoxyphenyl)ethenyl)-, (E)-

Participants

Reaction Steps

Substantially the same procedure as in Reference Example 70 was repeated using 3.00 g (15.1 mmol) of 5,6-diamino-1,3-diethyluracil and 3.20 g (16.7 mmol) of 4-ethoxycinnamic acid. Then, the resultant crude crystals were recrystallized from dioxane to give 2.97 g (yield 55%) of Compound 123 as pale yellow needles.

Provenance & Evidence