p-Bromocinnamic acid → 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(4-bromophenyl)ethenyl)-1,3-diethyl-, (E)-

Participants

Reaction Steps

Substantially the same procedure as in Reference Example 70 was repeated using 2.20 g (11.1 mmol) of 5,6-diamino-1,3-diethyluracil and 2.78 g (12.2 mmol) of 4-bromocinnamic acid. Then, the resultant crude crystals were recrystallized from tetrahydrofuran/water to give 930 mg (yield 22%) of Compound 141 as yellow columns.

Provenance & Evidence