HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 735839, compound → 1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(3-(trifluoromethoxy)phenyl)ethenyl)-, (E)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 735839 | HCID 735839 | — |
| Reactant | 5,6-Diamino-1,3-diethyluracil | HCID 4572133 | — |
| Product | 1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(3-(trifluoromethoxy)phenyl)ethenyl)-, (E)- | HCID 6448918 | 60% |
Reaction Steps
Substantially the same procedure as in Reference Example 70 was repeated using 1.00 g (5.05 mmol) of 5,6-diamino-1,3-diethyluracil and 1.29 g (5.56 mmol) of 3-trifluoromethoxy-cinnamic acid. Then, the resultant crude crystals were recrystallized from dioxane/water to give 1.19 g (yield 60%) of Compound 143 as white needles.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05543415 |
| Source dataset | uspto-grants-1996_08 |
| ORD ID | ord-427821ebdeb64aa2a29361f7fb788ea3 |
| Source note | uspto-grants-1996_08 |