HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → (S)-(-)-2-Nitro-1-(2-oxiranylmethyl)-1H-imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1-(3-Chloro-2-hydroxypropyl)-2-nitroimidazole | HCID 114542 | — |
| Product | (S)-(-)-2-Nitro-1-(2-oxiranylmethyl)-1H-imidazole | HCID 11768967 | — |
Reaction Steps
Alternatively, reaction of 0.56 g of (S)-(+)-(α-(chloromethyl)-2-nitro-1H-imidazole-1-ethanol with 3 mL of 10% aqueous sodium hydroxide at 25° C. for 30 minutes followed by further processing as above gives 0.3 g of the product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05543527 |
| Source dataset | uspto-grants-1996_08 |
| ORD ID | ord-870a3b14b942437a8e6f152377e48814 |
| Source note | uspto-grants-1996_08 |