Ethyl 5-fluoro-2-nitrobenzoate → HCID 22363000, compound

HRID 1077612Notes

Reaction equation

HRID 1077612 reaction equation
FC1C=CC([N+]([O-])=O)=C(C=1)C(OCC)=O.[F:16][C:17]1[CH:18]=[CH:19][C:20]([N+:29]([O-])=O)=[C:21]([CH:28]=1)[C:22]([O:24][CH2:25][CH2:26][CH3:27])=[O:23]>>[F:16][C:17]1[CH:28]=[C:21]([C:22]([O:24][CH2:25][CH2:26][CH3:27])=[O:23])[C:20]([NH2:29])=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 10987604Ethyl 5-fluoro-2-nitrobenzoateHCID 19432024HCID 19432024, compound

Product 1

HCID 22363000HCID 22363000, compound

Procedure

If the isomerically pure ethyl 5-fluoro-2-nitrobenzoate is replaced by aliquot parts of a correspondingly prepared, isomerically pure n-propyl 5-fluoro-2-nitrobenzoate, and the same procedure is employed, then the isomerically pure n-propyl 5-fluoroanthranilate is obtained in comparable yield and quality.

Workup

  1. customa correspondingly prepared

Sources & evidence

ORD record
ord-0814e9c620d940c1b7d83475a954c44a
Source dataset
uspto-grants-1996_08
Patent number
US05543550

Reaction notes

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