反应详情

To a solution of 1.2 g (5.0 mmol) of 6-bromo-1,2,3,4-tetrahydro-1,1-dimethylnaphthalene (Compound F) in 20 ml of CCl4 was added 0.97 g (5.5 mmol) of N-bromosuccinimide followed by 20 mg (0.08 mmol) of benzoylperoxide. The mixture was refluxed for 3 hours, filtered and the filtrate washed with water (5 ml). The organic phase was dried over MgSO4 and then concentrated in vacuo to yield the title compound as a pale yellow oil.

1. temperatureThe mixture was refluxed for 3 hours
2. filtrationfiltered
3. washthe filtrate washed with water (5 ml)
4. dry with materialThe organic phase was dried over MgSO4
5. concentrationconcentrated in vacuo