HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phloretin → HCID 70181280, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phloretin | HCID 4788 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 70181280 | HCID 70181280 | 67.5% |
Reaction Steps
Phloretin (25 mg) is dissolved in the minimum amount of methanol, diluted with water (3 ml) and treated with a slight excess of NaBH4. After 5 minutes the solution is carefully acidified, with ethyl acetate. The Organic phase is dried over Na2SO4 and evaporated to dryness to give 17 mg of dihydrophloretin as white powder, homogeneous on TLC analysis (silica gel, CHCl3 /MeOH/H2O 70:28:2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05545399 |
| Source dataset | uspto-grants-1996_08 |
| ORD ID | ord-e6a356067c3c4397b72f113997f80cc2 |
| Source note | uspto-grants-1996_08 |