Methyl iodide → 3-(4-Hexyloxy-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide

HRID 1077726Notes

Reaction equation

HRID 1077726 reaction equation
[CH3:1][I:2].[CH2:3]([O:9][C:10]1[C:14]([C:15]2[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=2)=[N:13][S:12][N:11]=1)[CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]>CC(C)=O>[I-:2].[CH2:3]([O:9][C:10]1[C:14]([C:15]2[CH:16]=[N+:17]([CH3:1])[CH:18]=[CH:19][CH:20]=2)=[N:13][S:12][N:11]=1)[CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 151801353-(4-(Hexyloxy)-1,2,5-thiadiazol-3-yl)pyridine

Product 1

HCID 189409483-(4-Hexyloxy-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of methyl iodide (0.5 ml, 7.5 mmol) and 3-(3-hexyloxy-1,2,5-thiadiazol-4-yl)pyridine (658 mg, 2.5 mmol) in acetone (5 ml) was stirred at room temperature for 18 h. The title compound precipitated from the solution and was collected by filtration to yield 0.81 g (80%).

Workup

  1. customThe title compound precipitated from the solution
  2. filtrationwas collected by filtration
  3. customto yield 0.81 g (80%)

Sources & evidence

ORD record
ord-1b5e48bd10334633b8cf6db56d34c7d1
Source dataset
uspto-grants-1996_08
Patent number
US05545638

Reaction notes

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